Antifungal Compound Library Formula Erythrocyte sedimentation rate, C-reactive protein, haemoglobin, white blood cell count, and platelet count were analysed consecutively by standard laboratory techniques at the Departments of Clinical Chemistry.Statistical methodsMean and standard deviation (SD) was used for descriptive purposes. This report focuses on results of electrocardiographic (ECG) recordings and the association between cardiac Antibacterial Compound Library supplier conduction system abnormalities and markers of disease activity and HLA B27 subtypes. The study was performed according to the Helsinki Declaration of 1975, revised in 1983, approved by the Regional Ethics Committee in Gothenburg and the patients gave written informed consent to participate.Ied through the patient records at three different departments of Rheumatology in Sweden, in Gothenburg (Sahlgrenska University Hospital), Bor and Alings . All patients fulfilled the modified New York criteria‘s for AS [12]. Exclusion criteria were psoriasis, inflammatory bowel disease, dementia, pregnancy, other severe diseases such as malignancy and difficulties in answering questionnaires. The medical records of all AS patients registered in the hospitals‘ databases were reviewed. The flow-chart for enrolment is shown in Figure 1. All patients meeting study criteria were asked to participate in this cross-sectional AS study investigating in particular some cardiac and skeletal consequences of the disease. For further information about the study design see also a previous report [14]. This report focuses on results of electrocardiographic (ECG) recordings and the association between cardiac conduction system abnormalities and markers of disease activity and HLA B27 subtypes. The study was performed according to the Helsinki Declaration of 1975, revised in 1983, approved by the Regional Ethics Committee in Gothenburg and the patients gave written informed consent to participate. The 151 patients who declined to participate or were excluded were on average slightly younger (46 ?13 years), but the sex distribution was the same among included and not included patients.Electrocardiographic recording and analysisThe patients underwent physical examination by the same physician (EK), including Bath Ankylosing Spondylitis Metrology Index (BASMI), and answered questionnaires about medical Natural Product Library site history, medication, Bath Ankylosing Spondylitis Disease Activity Index (BASDAI), and Bath Ankylosing Spondylitis Functional Index (BASFI) [15]. The PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/10454496 presence of the HLA-B27 antigen and its alleles HLA-B2701 to HLA-B2738 were assessed by HLA typing with sequence-specific oligonucleotide primers (PCRSSO) by LABType? (One Lambda, Inc, CA, USA) and use of the Luminex platform at the Department of Clinical Immunology and Transfusion Medicine, Sahlgrenska University Hospital. Erythrocyte sedimentation rate, C-reactive protein, haemoglobin, white blood cell count, and platelet count were analysed consecutively by standard laboratory techniques at the Departments of Clinical Chemistry.Statistical methodsMean and standard deviation (SD) was used for descriptive purposes. Univariate and forward stepwise multivariate linear and logistic regression analysis PubMed ID:https://www.ncbi.nlm.nih.gov/pubmed/18575713 was used to assess associations between the occurrence of conduction abnormalities and ECG measures with clinical, anthropometric and laboratory data. Chi-square test or Fisher‘s exact two-tailed test were used for comparison of proportions.Ied through the patient records at three different departments of Rheumatology in Sweden, in Gothenburg (Sahlgrenska University Hospital), Bor and Alings . All patients fulfilled the modified New York criteria‘s for AS [12].