In a Title Loaded From File context of intense human mobility, the challenge of asymptomatic infections is Title Loaded From File probably to be augmented, due to the fact symptomless migrants represent a mobile and silent reservoir of malaria infections. Considering it as an intervention via which data are systematically collected, analysed, and interpreted, to ensure that both symptomatic and asymptomatic instances are identified, triggering rapid action to prevent additional transmissionConclusion The Program for Elimination of Malaria in Brazil, launched in November 2015, is in alignment using the new Sustainable Development Agenda [194], and builds on a special momentum: the amount of malaria cases inside the nation has reached its lowest levels in 35 years, P. falciparum is very focal, and the geographic boundary of transmission has considerably shrunk. When the prospects for results are very good, challenges are numerous and varied. This paper discussed the challenges ahead, some already present, others a possibility. In light of the potential challenges, a handful of issues require some reflection. Very first, the promotion of collaboration between different government and private sectors (including, for example, education, agriculture, finance, urbanFerreira and Castro Malar J (2016) 15:Page 14 ofplanning, transportation, and environment), albeit typically difficult to obtain, is of paramount significance to add a development dimension to malaria control [195]. Brazil has already promoted essential initiatives in the context of agrarian reform and infrastructure projects in locations appropriate to malaria [196], but there is a require and an chance for more collaborations.Ederal levels. Migratory movements have critical malaria implications depending around the levels of immunity amongst migrants, the underlying patterns of transmission in sending and getting regions, the regional traits observed in places of origin and location, the individual expertise concerning the illness, plus the pattern of mobility [188, 189]. Human mobility is intense inside the Brazilian Amazon driven by new financial opportunities (e.g., mining, land availability) or by the will need to acquire goods and/or services [190]. Within a context of intense human mobility, the challenge of asymptomatic infections is probably to be augmented, considering the fact that symptomless migrants represent a mobile and silent reservoir of malaria infections. Additionally, human movements can facilitate the reintroduction of malaria in areas that have drastically lowered (and even eliminated) malaria.Ederal levels. Migratory movements have essential malaria implications based around the levels of immunity amongst migrants, the underlying patterns of transmission in sending and getting regions, the regional characteristics observed in areas of origin and destination, the individual information in regards to the illness, and also the pattern of mobility [188, 189]. Human mobility is intense in the Brazilian Amazon driven by new economic opportunities (e.g., mining, land availability) or by the need to obtain goods and/or services [190].Ederal levels. Migratory movements have important malaria implications depending around the levels of immunity amongst migrants, the underlying patterns of transmission in sending and receiving regions, the nearby characteristics observed in regions of origin and location, the individual know-how regarding the disease, along with the pattern of mobility [188, 189]. Human mobility is intense inside the Brazilian Amazon driven by new financial possibilities (e.g., mining, land availability) or by the want to obtain goods and/or solutions [190]. In a context of intense human mobility, the challenge of asymptomatic infections is likely to become augmented, because symptomless migrants represent a mobile and silent reservoir of malaria infections.